A contribution to the Kaleidoscope of Hope Foundation is a gift to the health and well-being of women everywhere.
Our mission is to raise funds for ovarian cancer research and increase awareness of the symptoms of this disease.
KOH 2015 Research GrantsAmong the many grant applications for funding of innovative ovarian cancer research projects, KOH has narrowed the pool of proposals to its final eight candidates. Applications have been received from leading researchers throughout the United States.
During its 14 year history, KOH has awarded over $2.6 million for ovarian cancer research. The Morristown-based organization continues its commitment to seeking better treatment options, early detection, and ultimately a cure for this disease by seeking out proposals from world class scientists exploring cutting edge therapies. Ovarian cancer remains the most deadly of all gynecological cancers, and most cases are diagnosed in late stage disease when treatment is far more difficult, and mortality rates are highest. This year’s finalists have been drawn from institutions across the United States
Award decisions will be announced in the next few months by the KOH Scientific Advisory Committee, which is comprised of distinguished scientists in the ovarian cancer research community.
We Remember, We Celebrate,
KOH hosts an evening of hope as researchers provide updates on the research they are performing with grants from KOH!
Read the Article Contribute to our Cause
New Genetic link to lethal ovarian cancer has potentially been identified
Aggressive Ovarian Cancer May Be Caused by a Single Gene MutationBy Jim Stallard, MA, Writer/Editor | Tuesday, April 1, 2014
Memorial Sloan Kettering researchers have identified a genetic mutation that appears to cause a rare but very aggressive type of ovarian cancer in young women. The discovery could be an important step toward developing the first effective treatments for the disease, called small cell carcinoma of the ovary, hypercalcemic type (SCCOHT). Funded initially by a charitable organization, the research is also an example of the powerful effect philanthropy can have on rare diseases.
“There are many examples of women in their late teens or early 20s dying quickly from this disease,” says gynecologic oncologist Douglas Levine, who led the research. “The median age at diagnosis is 23, and they usually die within two years — it’s devastating. Finding the cause and a possible target could be a major advance because current therapies have very little effect.”
....Using human cancer cells, Dr. Levine and colleagues then demonstrated that SMARCA4 plays a functional role in promoting or blocking cancer growth. Inactivating SMARCA4 increased cancer growth, while boosting its expression slowed it down. This buttresses the theory that the SMARCA4 mutation is key to the rare disease.
“I don’t know of many cancers where there’s one gene that is universally mutated and seems to be driving the disease,” Dr. Levine says. “One of our next steps will be to investigate whether this one mutation is actually sufficient to transform any type of ovarian cell into a cancer cell, or whether other factors are involved.”
KOH Announces 2014 HONORED RESEARCHERS Awardees
KOH proudly presents its 2014 Award Winning Researchers
Michael Goldberg, PhD of the Dana-Farber Cancer Institute, Harvard University (L) and Laura Dillon, Ph.D., Postdoctoral Fellow Department of Biochemistry and Molecular Genetics University of Virginia, School of Medicine (R)
KOH Grant Funds Innovative Research
Dogs help sniff out ovarian cancer in Pennsylvannia Study
Nov 18, 2013 KOH visited Penn Vet Working Dog facility. They watched as three dogs were being trained to pick out the ovarian cancer tissue sample.
KOH provided a grant to help fund this research.
In this Thursday, Aug. 1, 2013 photo, Jonathan Ball practices with Tsunami in the first round of training for a study that will eventually involve detecting cancerous tissue at Penn Vet Working Dog Center in Philadelphia.
Researchers trying to develop a diagnostic tool for ovarian cancer are hoping dogs' keen sense of smell will lead them down the right path.
An early detection device that combines old-fashioned olfactory skills, chemical analysis and modern technology could lead to better survival rates for the disease, which is particularly deadly because it's often not caught until an advanced stage.
The ovarian cancer detection study is being funded by an $80,000 grant from the Madison, N.J.-based Kaleidoscope of Hope Foundation
Click to Read Full AP Article
WINGS OF HOPE
KOH is honored that our Vice President, Carole Fagella, is the recipient of the Cancer Support Community of Central NJ's Spirit of Courage award this year. Carole's battle with O/C continues and so does her never ending activism in the fight against this disease and her tireless efforts to educate others about O/C.
KOH's Lynn Franklin (left) with Carole Fagella (right)
KOH has renewed its partnership with the Ovarian Cancer National Alliance in Wahington DC. Delegates from KOH will attend advocacy sessions in The House of Representatives and the Senate again in 2013 to promote national Ovarian Cancer initiatives on Capitol Hill.
KOH's Carole Fagella gives Award to US Senator Robert Menendez
Vice President, Carole Fagella, presented Senator Robert Menendez with an award from the Ovarian Cancer National Alliance in Washington DC in 2011. Carole has represented KOH as a delegate and lobbyist in the Senate and the House of Representatives for the past 5 years. She participates annually in Capitol Hill Advocacy Day with our partner organization, OCNA
At Right, Carole Fagella (3rd from left), pictured with her son , Alex (far right), and other OCNA delegates honor Senator Robert Menendez for his continued support of the ovarian cancer community . Senator Menendez was recognized with an outstanding achievement award by the OC National Alliance for his strong support of ovarian cancer initiatives on Capitol Hill
KOH Funds Grants
KOH Funded a Grant That is a Published Poster Display at the 2012 Society of Gynecologic Oncology and at the 2012 National Annual Meeting of the Association of Clinical Oncology
KOH's Scientific Advisory Board chooses our grant recipients with great care and knowledge. Proof lies with the American Society of Clinical Oncology's choice for a display at their 2012 National meeting presented by MSKCC researchers with funding from KOH - research which was supported by a grant from KOH! click to view summary
Pictured above is Dr. David Hyman, recipient of 2011 KOH Grant Award
KOH 2010 Grant Recipient Honored by SGO
Dr. Sarah Adams, of the University of Pennsyvania Medical Center, was honored by the Society of Gynecologic Oncologists for her research project at SGO's 2012 Annual Meeting. Dr. Adams presented a power point presentation outlining her research with BRCA tumors. Dr. Adam's ovarian cancer research was funded by a grant from KOH.
KOH is very proud of its Scientific Advisory Committee and the brilliant researchers it selects to give financial grants to each year.
Presentation of $15,000 check to Community Medical Center- Toms River
In 2012, KOH donated $15K to the Community Medical Center in Toms River, NJ.
Pictured above from Left to Right are: Kathy Lynch, Stephanie Bloom, Mariclaire Scott, Janice Carey
Stephanie Bloom is President and Chief Executive Officer at Community Medical Center-
This money donated by KOH will be used to assist with robotic gynecological oncology surgery for women!
Fourteen Years of Passionate Activism!
The Kaleidoscope of Hope Foundation (KOH) is a 501(c)(3) non-profit organization that raises funds and acts as the primary advocate for ovarian cancer activism in the New Jersey area. KOH was founded in 2000 by three ovarian cancer survivors who turned their experiences with ovarian cancer into passionate activism.
The hope in Kaleidoscope of Hope represents the difference that early diagnostic tests or disease-specific therapy can make in the lives of women and their families.
Since 2000, the Kaleidoscope of Hope Foundation has raised and awarded over $2.5 million to help fund research for early detection and new treatment options.
With a little bit of hope and your help, we can boost the survival rates of women affected by ovarian cancer and change lives. Learn more about KOH.
KOH is looking for men and women volunteers to help in the following areas:
- Identify and write grants
- Computer, social networking skills
- Event Planning
- Fundraising activities
Alicia's Message to you:
Watch this youtube video
Alicia's message to you
could save your life!
Can Dogs Detect
Cancer by Smell?
PBS News Special Report
Vet Program and Ffoster,
the dog sponsored by KOH!
Watch this PBS News Special
Features Dr. Otto of UPENN
and the training of dogs to
sniff out ovarian cancer.
Watch this News Update
Cathy's story is her personal
experience with ovarian
cancer. The video is
produced by the
WAI FOUNDATION, a new
ovarian cancer initiative and
website created by a daughter
whose mother survived late
stage ovarian cancer.
Visit their website and
their facebook page